Stem Cell Therapy for Scleroderma in Mexico

Scleroderma is an autoimmune disease that mainly affects the skin of the hands. Stem Cell therapy for Scleroderma is an optimal treatment option and is supported by many scientific researches as well.

Symptoms of Scleroderma

Signs and Symptoms of Scleroderma

Scleroderma can affect various tissues and organs in the body.

• Skin: 99% of patients who are suffering from this disease experiences skin hardening. Some may even develop patches. As the skin tightens, the movement of the limb is restricted.
• Digestive System: The different parts of the digestive tract can become affected by Scleroderma. Overall, the patient experiences difficulty in swallowing and extracting nutrients from the food.
• Fingers and Toes: Patient with Scleroderma may first develop Raynaud's disease where small blood vessels in the fingers and toes constrict due to low temperature. Due to this, the affected area turns blue due to lack of oxygen and this can also be painful at times.
• Heart, lungs or kidneys: These organs may stop functioning properly and the patient develops related problems.

How Stem Cells Can Help Scleroderma Patients?

Scleroderma is an autoimmune disease where the body cells start attacking other cells in the body. The stem cells, especially the hematopoietic stem cells (HSCT) can halt the scleroderma progression in patients.

According to a study published in January 2018, patients with scleroderma achieved long-term event-free survival with stem-cell transplantation as compared to standard of care therapy.

Methods of Stem Cells Administration

The stem cells used can be either autologous (extracted from the patient’s body) or allogenic (taken from a matched donor). These stem cells can be administered in three of the mentioned ways:

• Intravenous: The cells are infused via veins so as to expand the blood volumes in the central nervous system. This ensures that maximum cells reach the target area of therapy.
• Local: The cells are directly administered at the site of injury. This is done using a catheter-based delivery system.
• Sub-Cutaneous: The cells are administered in the fat layer of the skin. This therapy promotes regeneration of skin cells and is thus used for restructuring of skin tissues.